Partially hydrolyzed guar gum suppresses the progression of pulmonary arterial hypertension in a SU5416/hypoxia rat model

Autor: Takayuki J. Sanada, Koji Hosomi, Jonguk Park, Akira Naito, Seiichiro Sakao, Nobuhiro Tanabe, Jun Kunisawa, Koichiro Tatsumi, Takuji Suzuki
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Pulmonary Circulation, Vol 13, Iss 3, Pp n/a-n/a (2023)
Druh dokumentu: article
ISSN: 2045-8940
DOI: 10.1002/pul2.12266
Popis: Abstract This study investigated the effects of partially hydrolyzed guar gum (PHGG) on the development of pulmonary arterial hypertension using a SU5416/hypoxia rat model. Our results demonstrated that PHGG treatment suppressed the development of pulmonary hypertension and vascular remodeling with an altered gut microbiota composition.
Databáze: Directory of Open Access Journals