Bis-naphtho-γ-pyrones from Fungi and Their Bioactivities

Autor: Shiqiong Lu, Jin Tian, Weibo Sun, Jiajia Meng, Xiaohan Wang, Xiaoxiang Fu, Ali Wang, Daowan Lai, Yang Liu, Ligang Zhou
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: Molecules, Vol 19, Iss 6, Pp 7169-7188 (2014)
Druh dokumentu: article
ISSN: 1420-3049
DOI: 10.3390/molecules19067169
Popis: Bis-naphtho-γ-pyrones are an important group of aromatic polyketides derived from fungi. They have a variety of biological activities including cytotoxic, antitumor, antimicrobial, tyrosine kinase and HIV-1 integrase inhibition properties, demonstrating their potential applications in medicine and agriculture. At least 59 bis-naphtho-γ-pyrones from fungi have been reported in the past few decades. This mini-review aims to briefly summarize their occurrence, biosynthesis, and structure, as well as their biological activities. Some considerations regarding to synthesis, production, and medicinal and agricultural applications of bis-naphtho-γ-pyrones are also discussed.
Databáze: Directory of Open Access Journals