CLINICAL EFFICIENCY OF COMBINED AMINO-ACID COMPLEX USAGE IN COMPLEX TREATMENT OF PATIENTS WITH DIABETIC PERIPHERAL POLYNEYROPATHY
| Autor: | M. I. Shved, N. R. Makarchuk, L. P. Martynyuk |
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| Jazyk: | ukrajinština |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Vіsnik Naukovih Doslіdžen', Vol 0, Iss 3 (2017) |
| Druh dokumentu: | article |
| ISSN: | 1681-276X 2415-8798 |
| DOI: | 10.11603/2415-8798.2017.3.8082 |
| Popis: | Standard treatment of diabetic polyneuropathy, one of the most common diabetes mellitus complications, is effective, but only leads to a temporary clinical effect. The aim of the study – to increase the efficacy of treatment of neuropathic pain by incorporating Keltican drug into a complex therapy of diabetic polyneuropathy. Results and Discussion. 64 patients with type 2 diabetes, complicated by diabetic polyneuropathy were examined. Patients were compared into two groups: the control group consisted of 32 patients, who received standard treatment, 32 patients of another group received additionally Keltican (1 capsule three times a day for a month). The assessment and intensity of neuropathic pain was performed using a modified questionnaire DN 4. Positive clinical effect of treatment was observed in both groups after 12-day treatment, and was maintained for a month. But such effect was preserved after 3 and 6 months only in the group with Keltican appointment. Conclusions. Using the DN 4 questionnaire with a modified scale for evaluating the parameters of neuropathic pain can optimize the diagnosis of this complication in patients with diabetes mellitus. The inclusion of the Keltican in the standard complex therapy of diabetic polyneuropathy increases the clinical efficacy of neuropathic pain treatment and contributes to the preservation of the therapeutic effect for 6 months in 64.2 % of patients. |
| Databáze: | Directory of Open Access Journals |
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