Advancing HER2-low breast cancer management: enhancing diagnosis and treatment strategies

Autor: Borstnar Simona, Bozovic-Spasojevic Ivana, Cvetanovic Ana, Plavetic Natalija Dedic, Konsoulova Assia, Matos Erika, Popovic Lazar, Popovska Savelina, Tomic Snjezana, Vrdoljak Eduard
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Radiology and Oncology, Vol 58, Iss 2, Pp 258-267 (2024)
Druh dokumentu: article
ISSN: 1581-3207
DOI: 10.2478/raon-2024-0030
Popis: Recent evidence brought by novel anti-human epidermal growth factor receptor 2 (HER2) antibody-drug conjugates is leading to significant changes in HER2-negative breast cancer (BC) best practices. A new targetable category termed ‘HER2-low’ has been identified in tumors previously classified as ‘HER2-negative’. Daily practice in pathology and medical oncology is expected to align to current recommendations, but patient access to novel anticancer drugs across geographies might be impeded due to local challenges.
Databáze: Directory of Open Access Journals