Rationale and study design for one-stop assessment of renal artery stenosis and renal microvascular perfusion with contrast-enhanced ultrasound for patients with suspected renovascular hypertension
| Autor: | Jun-Hong Ren, Na Ma, Si-Yu Wang, You-Jing Sun, Yue-Wei Zhang, Fa-Jin Guo, Yong-Jun Li, Tian-Hui Li, Hu Ai, Wen-Duo Zhang, Peng Li, Wei-Hua Ma, Ning-Ning Wang |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: | |
| Zdroj: | Chinese Medical Journal, Vol 132, Iss 1, Pp 63-68 (2019) |
| Druh dokumentu: | article |
| ISSN: | 0366-6999 2542-5641 00000000 |
| DOI: | 10.1097/CM9.0000000000000002 |
| Popis: | Abstract. Background:. Renal artery stenosis (RAS) is always associated with abnormalities in renal microvascular perfusion (RMP). However, few imaging methods can simultaneously evaluate the degree of luminal stenosis and RMP. Thus, this study will aim to evaluate the feasibility of using contrast-enhanced ultrasound (CEUS) for assessing both RAS and RMP to achieve a one-stop assessment of patients with suspected renovascular hypertension. Methods:. This will be a single-center diagnostic study with a sample size of 440. Patients with chronic kidney disease (CKD) and suspected of having resistant hypertension will be eligible. Patients with Stages 1–3 CKD will undergo CEUS and computed tomography (CT) angiography (CTA). Values obtained by CEUS and CTA for diagnosing low-grade (lumen reduced by |
| Databáze: | Directory of Open Access Journals |
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