Autor: |
Deyu Hu, Qianzhu Li, Linhong Jin, Song Yang, Huiping Zhang, Baoan Song, Guiping Ouyang |
Jazyk: |
angličtina |
Rok vydání: |
2005 |
Předmět: |
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Zdroj: |
Molecules, Vol 10, Iss 10, Pp 1351-1357 (2005) |
Druh dokumentu: |
article |
ISSN: |
1420-3049 |
DOI: |
10.3390/10101351 |
Popis: |
A facile synthesis of 3-methylthio-3-arylamino-2-cyanoacrylates from 3,3-dimethylthioacrylate and aromatic amines or amino pyridines has been achieved in moderate to high yields (64.0% ~ 93.5%) in 30 minutes at 50°C under microwave irradiation. This method is very simple and the reaction conditions are mild, environmentally friendly and more importantly, quick. In the 3-(4,5-dimethylthiazol- 2-yl)-2,5-diphenyltetrazolium bromide (MTT) test, some of the title compounds were found to possess good antiproliferation activity towards PC3 cells. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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