| Autor: |
DANICA AGBABA, DOBRILA ZIVANOV-STAKIC, SOTE VLADIMIROV, OLIVERA CUDINA |
| Jazyk: |
angličtina |
| Rok vydání: |
2000 |
| Předmět: |
|
| Zdroj: |
Journal of the Serbian Chemical Society, Vol 65, Iss 9, Pp 645-648 (2000) |
| Druh dokumentu: |
article |
| ISSN: |
0352-5139 |
| Popis: |
The proposed method for the determination of fluocortolone is based on the formation of a stable, yellow coloured hydrazone product with 1,4-dihydrazinophthalazine as the reagent. Heating at 85°C for 2 h was found to be necessary to ensure optimal hydrazone formation in acidified 1-propanol as the solvent. The detection limit was 1.2 µg/ml. This method when applied for the determination of fluocortolone in pharmaceutical formulations gave precise and reproducible results. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
