Research progress on human endometrium decidualization In vitro cell models

Autor:	Zhi-Jing Tang, Hai-Yun Guan, Lu Wang, Wei Zhang
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	cyclic adenosine monophosphate decidualization endometrium estrogen in vitro cell model progestogen Immunologic diseases. Allergy RC581-607 Diseases of the endocrine glands. Clinical endocrinology RC648-665
Zdroj:	Reproductive and Developmental Medicine, Vol 5, Iss 2, Pp 119-127 (2021)
Druh dokumentu:	article
ISSN:	2096-2924 2589-8728
DOI:	10.4103/2096-2924.320882
Popis:	Decidualization is a special type of differentiation of endometrial stromal cells into secretory decidualized cells, which is closely related to the occurrence of menstruation and establishment of pregnancy. Decidualization abnormalities can cause female infertility and abortion, and the decidualization model in vitro is an important tool for studying relevant mechanisms. This article summarizes several in vitro decidualization models in recent research from three aspects, including the selection of model cells and culture systems, evaluation of decidualization markers, and induction schemes. These models can be appropriately selected and applied in specific endometrium-related disease models, such as endometriosis, recurrent pregnancy loss, and preeclampsia.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/767c554c85ab41bbaef519672b1273a3 Zobrazit plný text záznamu View record in DOAJ