| Autor: |
Yu Sun, Hao Tang, Shuang Du, Yang Chen, Zheyuan Ou, Mei Zhang, Zhuoru Chen, Zhiwei Tang, Dongjun Zhang, Tianyi Chen, Yanyi Xu, Jiufeng Li, Dan Norback, Jamal Hisham Hashim, Zailina Hashim, Jie Shao, Xi Fu, Zhuohui Zhao |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
Eco-Environment & Health, Vol 2, Iss 4, Pp 208-218 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2772-9850 |
| DOI: |
10.1016/j.eehl.2023.08.001 |
| Popis: |
Indoor microorganisms impact asthma and allergic rhinitis (AR), but the associated microbial taxa often vary extensively due to climate and geographical variations. To provide more consistent environmental assessments, new perspectives on microbial exposure for asthma and AR are needed. Home dust from 97 cases (32 asthma alone, 37 AR alone, 28 comorbidity) and 52 age- and gender-matched controls in Shanghai, China, were analyzed using high-throughput shotgun metagenomic sequencing and liquid chromatography-mass spectrometry. Homes of healthy children were enriched with environmental microbes, including Paracoccus, Pseudomonas, and Psychrobacter, and metabolites like keto acids, indoles, pyridines, and flavonoids (astragalin, hesperidin) (False Discovery Rate |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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