| Autor: |
Hirofumi Ota, Katsuki Danno, Katsuya Ohta, Tae Matsumura, Takamichi Komori, Shu Okamura, Miho Okano, Atsuhiro Ogawa, Hiroshi Tamagawa, Mamoru Uemura, Chu Matsuda, Tsunekazu Mizushima, Hirofumi Yamamoto, Riichiro Nezu, Yuichiro Doki, Hidetoshi Eguchi |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Journal of the Anus, Rectum and Colon, Vol 4, Iss 3, Pp 114-121 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2432-3853 |
| DOI: |
10.23922/jarc.2019-043 |
| Popis: |
Objectives: The efficacy of negative pressure wound therapy (NPWT) and its application to severely contaminated wounds sustained during surgery remain to be established. Here, we evaluated the efficacy of utilizing NPWT until delayed primary closure (DPC) by assessing the infection rates in patients with lower gastrointestinal perforations. Methods: This prospective multicenter cohort study included 56 patients that underwent abdominal surgery for lower gastrointestinal perforations in eight institutions, from February 2016 to May 2017. All patients received NPWT after surgery before attempting DPC. The extent of peritonitis was categorized according to Hinchey's classification. Patients in stages II-IV were included. Results: Five patients had surgical site infections (SSIs) during NPWT and did not receive a DPC (9%). Of the 51 patients that received DPCs, 44 had no infection (91%) and 7 developed SSIs after the DPC (13.7%). For stages II, III, and IV, the SSI rates were 0%, 22.6%, and 35.7%, respectively; the median (range) times to wound healing were 15 (10-36), 19 (11-99), and 19 (10-53) days, respectively. There were no significant differences between the stages. Conclusions: NPWT followed by DPC resulted in low infection rates in each peritonitis stage. This approach appears promising as an alternative to traditional DPC alone for treating lower gastrointestinal perforations. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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