Pharmacogenetics and Age-Related Macular Degeneration

Autor: Stephen G. Schwartz, Milam A. Brantley
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: Journal of Ophthalmology, Vol 2011 (2011)
Druh dokumentu: article
ISSN: 2090-004X
2090-0058
DOI: 10.1155/2011/252549
Popis: Pharmacogenetics seeks to explain interpatient variability in response to medications by investigating genotype-phenotype correlations. There is a small but growing body of data regarding the pharmacogenetics of both nonexudative and exudative age-related macular degeneration. Most reported data concern polymorphisms in the complement factor H and age-related maculopathy susceptibility 2 genes. At this time, the data are not consistent and no definite conclusions may be drawn. As clinical trials data continue to accumulate, these relationships may become more apparent.
Databáze: Directory of Open Access Journals
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