Patient characteristics, burden and pharmacotherapy of treatment-resistant schizophrenia: results from a survey of 204 US psychiatrists

Autor:	Christoph U. Correll, Thomas Brevig, Cecilia Brain
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	Antipsychotics Clozapine Demography Treatment resistance Hallucinations Humans Psychiatry RC435-571
Zdroj:	BMC Psychiatry, Vol 19, Iss 1, Pp 1-12 (2019)
Druh dokumentu:	article
ISSN:	1471-244X
DOI:	10.1186/s12888-019-2318-x
Popis:	Abstract Background Minimal/non-response to antipsychotic treatment, and persistent positive symptoms despite treatment, are common among patients with schizophrenia. The aim of this study was to characterize a US treatment-resistant schizophrenia (TRS) population in terms of patient demographics, burden of symptoms, treatment history, and factors influencing therapeutic choice. Methods In an online survey, 204 psychiatrists self-selected and completed three patient records: two TRS and one schizophrenia (‘non-TRS’). Results Respondents reported that 29.5% of their schizophrenia caseload had TRS. Selected TRS (n = 408) vs non-TRS (n = 204) patients were more likely to be unemployed (74.5% vs 45.1%, p
Databáze:	Directory of Open Access Journals
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