| Autor: |
Zahra Heidari, Bita Moudi, Hamidreza Mahmoudzadeh-Sagheb, Mehrnoosh Moudi |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
Head & Face Medicine, Vol 13, Iss 1, Pp 1-8 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
1746-160X |
| DOI: |
10.1186/s13005-017-0148-y |
| Popis: |
Abstract Background Chronic Periodontitis (CP) is a common inflammatory disease affects supporting tissues of the teeth and can lead to tooth loss. The objective of this study was to determine the relationship between polymorphisms in the IL-28B gene and chronic periodontitis in an Iranian population. Methods Two hundred and ten CP patients and one hundred healthy subjects were enrolled in the present case-control study. The rs12979860 and rs8099917 SNPs were identified using RFLP and T-ARMS-PCR methods respectively. Results SNP analysis revealed that the G allele of rs8099917 SNP and T allele of rs12979860 SNP increased susceptibility to CP compared to the A allele and C allele (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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