Male pseudohermaphroditism in dogs: three case reports
| Autor: | M.R. Alam, Y.G. Cho, S.J. Cho, J.I. Lee, H.B. Lee, H.J. Tae, I.S. Kim, N.S. Kim |
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| Jazyk: | angličtina |
| Rok vydání: | 2007 |
| Předmět: | |
| Zdroj: | Veterinární Medicína, Vol 52, Iss 2, Pp 74-78 (2007) |
| Druh dokumentu: | article |
| ISSN: | 0375-8427 1805-9392 34736468 |
| DOI: | 10.17221/2056-VETMED |
| Popis: | Three Cocker Spaniel dogs, 2-3 months old, weighing 3-4 kg, were presented to the Chonbuk Animal Medical Centre, Chonbuk National University, with intersex anomalies. Physical, radiological, gross, histological, hormonal and cytogenetic studies were performed. Physical examination of the external genitalia revealed that the dogs possessed the vulva with an enlarged clitoris protruding from the vulvar juncture and the scrotum with an undescended testis in Case 1 and 2, and both testes remained undescended in Case 3. Hyperoestrogenaemia and low testosterone serum concentrations were found. Laparotomy revealed persistent Mullerian ducts (PMD) in Case 1 and 2, and abdominally located testicle(s) in all the cases. Histological examinations of the gonads revealed inactive seminiferous tubules. Cytogenetic analysis showed 78XY male karyotype in Case 1 and 2, whereas Case 3 showed 79XX female karyotype. The congenital defects were diagnosed as male pseudohermaphroditism (MPH) and PMD in Case 1 and 2, and XX sex reversal MPH in Case 3. |
| Databáze: | Directory of Open Access Journals |
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