A prospective cohort study of cutaneous leishmaniasis risk and opium addiction in south eastern Iran.

Autor: Mohammad Reza Aflatoonian, Iraj Sharifi, Maryam Hakimi Parizi, Ali Reza Fekri, Behnaz Aflatoonian, Maryam Sharifi, Ahmad Khosravi, Ali Khamesipour, Hamid Sharifi
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: PLoS ONE, Vol 9, Iss 2, p e89043 (2014)
Druh dokumentu: article
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0089043
Popis: Opium addiction and cutaneous leishmaniasis (CL) are endemic in different parts of Iran, particularly in Bam, where a massive earthquake occurred. This study was designed to compare the incidence rate and severity of CL cases among opium addicted and non-addicted individuals in south-eastern Iran. This study was carried out as a prospective cohort by active house-to-house visits of 1,481 habitants in Bam. CL cases were confirmed by smear and identification of Leishmania species was performed using nested-PCR. The data was analyzed by χ(2) and t-tests, using SPSS software and also Kaplan-Meier survival curve and long-rank test in Stata 11.2 and P
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