Factors Associated with Treatment Prescription to Pulmonary Tuberculosis Contacts in Catalonia (2019–2021): A Population-Based Epidemiological Study

Autor: Ángela Domínguez, Núria Soldevila, Diana Toledo, Ignasi Parrón, Joan-Pau Millet, Irene Barrabeig, Pere Godoy, on behalf of Transmission of Tuberculosis in Catalonia (Spain) Working Group
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Vaccines, Vol 11, Iss 12, p 1800 (2023)
Druh dokumentu: article
ISSN: 2076-393X
DOI: 10.3390/vaccines11121800
Popis: In countries with low tuberculosis (TB) incidence, the systematic testing and treatment of latent TB infection (LTBI) in contacts of pulmonary TB index cases is the standard of care. The objective of this study, conducted in Catalonia over 2019–2021, was to assess the factors associated with LTBI treatment prescription to close contacts of pulmonary TB index cases. In this population-based epidemiological study of LTBI prevalence among pulmonary TB contacts between 2019 and 2021, multiple logistic backward stepwise regression was used to identify the factors associated with treatment prescription, for which the adjusted odds ratio (aOR) and 95% confidence intervals (CI) were calculated. A total of 1487 LTBI contacts of 542 pulmonary TB index cases were studied, 80.6% of whom received a prescription. The factors associated with LTBI treatment prescription were exposure ≥6 h/day (aOR 14.20; 95% CI 5.22–38.66) and exposure
Databáze: Directory of Open Access Journals