Contribution of the Lung to the Genesis of Cheyne‐Stokes Respiration in Heart Failure: Plant Gain Beyond Chemoreflex Gain and Circulation Time

Autor: Alberto Giannoni, Francesco Gentile, Alessandro Navari, Chiara Borrelli, Gianluca Mirizzi, Giosuè Catapano, Giuseppe Vergaro, Francesco Grotti, Monica Betta, Massimo F. Piepoli, Darrel P. Francis, Claudio Passino, Michele Emdin
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 13 (2019)
Druh dokumentu: article
ISSN: 2047-9980
DOI: 10.1161/JAHA.119.012419
Popis: Background The contribution of the lung or the plant gain (PG; ie, change in blood gases per unit change in ventilation) to Cheyne‐Stokes respiration (CSR) in heart failure has only been hypothesized by mathematical models, but never been directly evaluated. Methods and Results Twenty patients with systolic heart failure (age, 72.4±6.4 years; left ventricular ejection fraction, 31.5±5.8%), 10 with relevant CSR (24‐hour apnea‐hypopnea index [AHI] ≥10 events/h) and 10 without (AHI
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