Assessing the effects of ultraviolet radiation, residential greenness and air pollution on vitamin D levels: A longitudinal cohort study in China

Autor: Haofan Zhang, Anna Zhu, Linxin Liu, Yi Zeng, Riyang Liu, Zongwei Ma, Miaomiao Liu, Jun Bi, John S. Ji
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Environment International, Vol 169, Iss , Pp 107523- (2022)
Druh dokumentu: article
ISSN: 0160-4120
DOI: 10.1016/j.envint.2022.107523
Popis: Vitamin D metabolism is essential in aging and can be affected by multiple environmental factors. However, most studies conducted single exposure analyses. We aim to assess the individual and combined effects of ultraviolet (UV) radiation, residential greenness, fine particulate matter (PM2.5), and ozone (O3) on vitamin D levels in a national cohort study of older adults in China. We used the 2012 and 2014 Chinese Longitudinal Healthy Longevity Survey data, and measured the environmental exposure in the same year. We interpolated the UV radiation from monitoring stations, measured residential greenness through satellite-derived Normalized Difference Vegetation Index (NDVI), modeled PM2.5 with satellite data, and estimated O3 using machine learning. We dichotomized serum 25-hydroxy vitamin D (25(OH)D), the primary circulating form of vitamin D, into non-deficiency (≥50 nmol/L) and deficiency (
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