| Autor: |
Alireza Akhavan Rezayat, Amirmohammad Soleimanian, Neda Kamandi, Mohammad Aslzare, Mohammad Mustafa Shaikh Zada |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Health Science Reports, Vol 6, Iss 7, Pp n/a-n/a (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2398-8835 |
| DOI: |
10.1002/hsr2.1431 |
| Popis: |
Abstract Background and Aims Varicocele is one of the most common causes of male infertility in which testicular function is progressively damaged. This study aims to investigate the effect of varicocelectomy and mast cell stabilizers on reducing sperm DNA fragmentation in infertile patients with varicocele. Methods In this randomized clinical trial, after obtaining ethical approval and informed consent, infertile patients with varicocele were randomly assigned to three groups: varicocelectomy, 1 mg ketotifen, and varicocelectomy plus with 1 mg ketotifen for 3‐month follow‐up. Semen analysis and estimation of DNA fragmentation index (DFI) were obtained from all people in the studied time periods. Results In this study, 420 infertile patients with varicocele were included with an average age of 31.6 years. The results showed that sperm morphology, sperm motility, sperm count, and sperm DFI had significant differences after the intervention (p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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