Conjunctival Impression Cytology and Tear Film Changes in Sarcoidosis: A Subjective and Objective Diagnosis Study

Autor: Özgür Eroğul, Aydın Balcı, Hamidu Hamisi Gobeka, Neriman Efe, Müberra Akdoğan, Ayşe Yeşim Oral, Mustafa Doğan, Çiğdem Özdemir, Murat Kaşıkçı, Sinan Saraçlı
Jazyk: English<br />Turkish
Rok vydání: 2023
Předmět:
Zdroj: Türk Oftalmoloji Dergisi, Vol 53, Iss 4, Pp 200-205 (2023)
Druh dokumentu: article
ISSN: 1300-0659
2147-2661
DOI: 10.4274/tjo.galenos.2022.58153
Popis: Objectives:To evaluate sarcoidosis-induced tear film changes using subjective and objective diagnostic tests, particularly conjunctival impression cytology (IC), and to compare the results with healthy individuals.Materials and Methods:This study evaluated clinical data collected between January 2019 and January 2021 from 57 right eyes of 57 sarcoidosis patients without ocular involvement (Group 1) and 33 right eyes of 33 healthy individuals with similar demographic characteristics (Group 2). The Schirmer I test, tear break-up time (TBUT), fluorescein staining, and conjunctival IC were all performed as part of the conjunctival and corneal examinations following a thorough ophthalmological examination. The Ocular Surface Disease Index (OSDI) was used to assess subjective ocular symptoms.Results:The mean ages in Groups 1 and 2 were 49.26±3.18 and 51.91±2.89 years, respectively (p=0.720). The mean Schirmer I test, TBUT, and OSDI scores differed significantly (p
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