Short-term results of interventional therapy for infants (7–36 months old) with patent ductus arteriosus and moderate-to-severe pulmonary hypertension: a retrospective study

Autor: Yue Shu, Yilong Guo, Xiaoqi Wang, Dexing Zhou
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Journal of Cardiothoracic Surgery, Vol 15, Iss 1, Pp 1-7 (2020)
Druh dokumentu: article
ISSN: 1749-8090
DOI: 10.1186/s13019-020-01110-5
Popis: Abstract Background Patent ductus arteriosus (PDA) is a common congenital heart disease. Interventional therapy is an important treatment for PDA. Nevertheless, few studies have investigated the safety and effectiveness of interventional therapy for infants (age, 0–36 months) with PDA and moderate-to-severe pulmonary hypertension. Therefore, this study aimed to analyze the short-term (6 months) results and interventional therapy experience for infants with PDA and moderate-to-severe pulmonary hypertension. Methods Clinical records, echocardiographic data, and angiocardiography data of 28 infants (age, 7–36 months) who underwent interventional therapy for PDA and moderate-to-severe pulmonary hypertension between December 2011 and January 2017 at our hospital were retrospectively analyzed. All infants were treated using an Amplatzer occluder with local and deep sedation anesthesia under radiographic guidance. Results Infants with PDA and moderate-to-severe pulmonary hypertension had poor growth. Trace residual shunts were found in two infants immediately after procedure; both had disappeared by 6 months after procedure. No significant interventional therapy-related complications occurred in the other cases. Pulmonary systolic pressure, left atrial dimension, and left ventricular end-diastolic dimension immediately after interventional therapy and 6 months later were lower than the preoperative levels (P
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