Clinical observation of a complete clinical, radiological and pathomorphological response in a patient with locally advanced gastric adenocarcinoma after neoadjuvant therapy

Autor: Diana Yu. Mironova, Vitaliy Yu. Skoropad, Tatev A. Agababyan, Natalya K. Silanteva, Ekaterina S. Zhavoronkova, Sergey A. Ivanov, Andrey D. Kaprin
Jazyk: English<br />Russian
Rok vydání: 2024
Předmět:
Zdroj: Клинический разбор в общей медицине, Vol 5, Iss 7, Pp 6-11 (2024)
Druh dokumentu: article
ISSN: 2713-2552
DOI: 10.47407/kr2024.5.7.00442
Popis: Stomach cancer is an aggressive disease and represents a global health problem. Currently, more than 50% of patients with a newly diagnosed stomach cancer have a locally advanced process that requires a combined approach – a combination of surgical treatment and neoadjuvant/perioperative therapy. In a number of patients, after neoadjuvant therapy, there is a marked or even complete regression of the tumor; the prognosis of the disease, as well as the need for adjuvant therapy in this category of patients is the subject of discussion. This paper demonstrates the clinical observation of a complete clinical, radiological and morphological response after neoadjuvant therapy (2 cycles of chemotherapy FLOT + chemoradiotherapy), as well as long-term relapse-free survival in a patient with locally advanced gastric cancer.
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