Real-world evaluation of perception, convenience and anticoagulant treatment satisfaction of patients with atrial fibrillation switched from long-term vitamin K antagonist treatment to dabigatran

Autor: Eue-Keun Choi, Young-Soo Lee, Alan Koay Choon Chern, Panyapat Jiampo, Aurauma Chutinet, Dicky Armein Hanafy, Prabhav Trivedi, Dongmei Zhai, Yong Seog Oh
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Open Heart, Vol 7, Iss 2 (2020)
Druh dokumentu: article
ISSN: 2020-0013
2053-3624
DOI: 10.1136/openhrt-2020-001343
Popis: Background and purpose Real-world data about treatment convenience and satisfaction in Asian non-valvular atrial fibrillation (NVAF) patients after switching from vitamin K antagonists (VKAs) to non-VKA oral anticoagulants were evaluated.Methods In this non-interventional study involving 49 sites across five countries in Southeast Asia and South Korea, 379 stable NVAF patients who switched from VKA therapy to dabigatran during routine clinical practice were recruited and followed up for 6 months. Treatment convenience and satisfaction were evaluated using Perception on Anticoagulant Treatment Questionnaire-2 (PACT-Q2). Through post hoc analysis, factors associated with improved treatment convenience scores at visit 2 were described.Results Treatment convenience and satisfaction significantly improved after switching from VKAs to dabigatran at visit 2 and visit 3 (convenience: p80th percentile) response on treatment convenience were female sex, younger age (
Databáze: Directory of Open Access Journals