Ni/Co-Catalyzed Homo-Coupling of Alkyl Tosylates

Autor:	Kimihiro Komeyama, Ryusuke Tsunemitsu, Takuya Michiyuki, Hiroto Yoshida, Itaru Osaka
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	homo-coupling SN2-type oxidative addition transalkylation alkyl tosylates cobalt catalyst nickel catalyst Organic chemistry QD241-441
Zdroj:	Molecules, Vol 24, Iss 8, p 1458 (2019)
Druh dokumentu:	article
ISSN:	1420-3049
DOI:	10.3390/molecules24081458
Popis:	A direct reductive homo-coupling of alkyl tosylates has been developed by employing a combination of nickel and nucleophilic cobalt catalysts. A single-electron-transfer-type oxidative addition is a pivotal process in the well-established nickel-catalyzed coupling of alkyl halides. However, the method cannot be applied to the homo-coupling of ubiquitous alkyl tosylates due to the high-lying σ*(C–O) orbital of the tosylates. This paper describes a Ni/Co-catalyzed protocol for the activation of alkyl tosylates on the construction of alkyl dimers under mild conditions.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/d75addd3aceb450c9a1c7f367334a36f Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
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