| Autor: |
Eickner Thomas, Teske Michael, Rekowska Natalia, Senz Volkmar, Schmitz Klaus-Peter, Grabow Niels |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Current Directions in Biomedical Engineering, Vol 7, Iss 2, Pp 692-695 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2364-5504 |
| DOI: |
10.1515/cdbme-2021-2176 |
| Popis: |
For the investigation of in vitro drug release, methods have been used in which samples of drug delivery systems are immersed in release medium. The medium is used to measure drug concentration via chromatography or photometry. These systems are suitable to investigate the drug release of different systems or to simulate tissue environments. When considering predominantly humid regions, e.g. for drug release into the cochlea through the round window membrane by a drug delivery system placed at that membrane, reproducible in vitro determination of drug release becomes particularly challenging. In this study the development of a system is reported that allows the investigation of the in vitro drug release simulating such conditions. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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