| Autor: |
Avan Arif Ahmad, Zohreh Rahimi, Asad Vaisi-Raygani |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Avicenna Journal of Medical Biochemistry, Vol 10, Iss 2, Pp 95-100 (2022) |
| Druh dokumentu: |
article |
| ISSN: |
2345-4113 |
| DOI: |
10.34172/ajmb.2022.2389 |
| Popis: |
Background: Obesity is defined as excessive fat accumulation in the adipose tissue and peripheral organs. The Kelch-like ECH-associated protein 1 (Keap1) is involved in cellular protection in obesity. Objectives: The objectives of this study were to detect the association of Keap1 rs11085735 variants with the risk of obesity in relation to anthropometric parameters and lipid profile in a population from the Kurdistan of Iraq. Methods: A total of 265 volunteers (134 females and 131 males) were randomly selected. According to the body mass index (BMI), individuals were divided into subjects with normal BMI (131 healthy individuals) and obese subjects (134 obese volunteers). Anthropometry and lipid profile parameters were measured in these volunteers and Keap1 rs11085735 variants were identified by the polymerase chain reaction (PCR) followed by digestion with HinfI restriction enzyme. Results: Triglycerides and low-density lipoprotein cholesterol (LDL-C) serum levels were significantly higher (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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