Evaluation of coronary artery lesion in men with osteopenic syndrome and coronary artery disease
| Autor: | A N Kokov, E B Maliuta, V L Masenko, A A Sigareva, V B Fanaskov, R S Tarasov, T A Raskina, I A Shibanova, O L Barbarash |
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| Jazyk: | ruština |
| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | Терапевтический архив, Vol 86, Iss 3, Pp 65-70 (2014) |
| Druh dokumentu: | article |
| ISSN: | 0040-3660 2309-5342 |
| Popis: | AIM: To examine the relation between coronary atherosclerosis (CA), coronary artery calcification (CAC), and bone mineral density (BMD) in men with coronary artery disease (CAD)/MATERIAL AND METHODS: The investigation included 74 males aged 60.1 (range, 55-70) years with verified CAD. All the patients underwent X-ray contrast-enhanced selective coronary angiography and coronary artery calcium score (CS) and BMD measurements by osteodensitometry. The severity of a coronary artery lesion was evaluated using the SYNTAX score. According to the T score, the patients were divided into 3 groups: 1) 23 patients with osteoporosis (OP), 2) 30 patients with osteopenia, and 3) 21 patients with normal BMD/RESULTS: Osteopenic syndrome (OS) (OP and osteopenia) was found in 71.6% of the patients with angiographically confirmed CAD. Single-vessel lesion in the coronary bed (CB) was more frequently recorded in the normal BMD group than in the OP one (p=0.023). Severe CB lesion was more common for the patients with OP (p=0.029). There were statistically significant differences between the osteopenia and normal BMD groups in the severe degree of CB lesion (p=0.042). Differences were noted in total CS between Groups 1 and 2 (p=0.0122). CS significantly correlated with the severity of CA lesion according to the SYNTAX score (r=0.53; p=0.002)/CONCLUSION: Severe CB lesion in males correlates with CAC and is associated with decreased BMD, suggesting the commonness of the pathogenetic components of AS and OS. |
| Databáze: | Directory of Open Access Journals |
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