| Autor: |
Michael T Yin, Ruijun Chen, George Hripcsak, Magdalena E Sobieszczyk, Sherif M Shoucri, Lawrence Purpura, Clare DeLaurentis, Matthew A Adan, Deborah A Theodore, Alexandria Lauren Irace, Shelief Y Robbins-Juarez, Apurva M Khedagi, Daniel Letchford, Amro A Harb, Lillian M Zerihun, Kate E Lee, Karen Gambina, Max C Lauring, Noah Chen, Colin P Sperring, Sanket S Mehta, Ellen L Myers, Hueyjong Shih, Michael G Argenziano, Samuel L Bruce, Cody L Slater, Jonathan R Tiao, Karthik Natarajan, Delivette Castor, Jason E Zucker |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
BMJ Open, Vol 11, Iss 6 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2044-6055 |
| DOI: |
10.1136/bmjopen-2021-049488 |
| Popis: |
Objective To characterise the long-term outcomes of patients with COVID-19 admitted to a large New York City medical centre at 3 and 6 months after hospitalisation and describe their healthcare usage, symptoms, morbidity and mortality.Design Retrospective cohort through manual chart review of the electronic medical record.Setting NewYork-Presbyterian/Columbia University Irving Medical Center, a quaternary care academic medical centre in New York City.Participants The first 1190 consecutive patients with symptoms of COVID-19 who presented to the hospital for care between 1 March and 8 April 2020 and tested positive for SARS-CoV-2 on reverse transcriptase PCR assay.Main outcome measures Type and frequency of follow-up encounters, self-reported symptoms, morbidity and mortality at 3 and 6 months after presentation, respectively; patient disposition information prior to admission, at discharge, and at 3 and 6 months after hospital presentation.Results Of the 1190 reviewed patients, 929 survived their initial hospitalisation and 261 died. Among survivors, 570 had follow-up encounters (488 at 3 months and 364 at 6 months). An additional 33 patients died in the follow-up period. In the first 3 months after admission, most encounters were telehealth visits (59%). Cardiopulmonary symptoms (35.7% and 28%), especially dyspnoea (22.1% and 15.9%), were the most common reported symptoms at 3-month and 6-month encounters, respectively. Additionally, a large number of patients reported generalised (26.4%) or neuropsychiatric (24.2%) symptoms 6 months after hospitalisation. Patients with severe COVID-19 were more likely to have reduced mobility, reduced independence or a new dialysis requirement in the 6 months after hospitalisation.Conclusions Patients hospitalised with SARS-CoV-2 infection reported persistent symptoms up to 6 months after diagnosis. These results highlight the long-term morbidity of COVID-19 and its burden on patients and healthcare resources. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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