Review of targeted therapy in chronic lymphocytic leukemia: what a radiologist needs to know about CT interpretation

Autor: Babina Gosangi, Matthew Davids, Bhanusupriya Somarouthu, Francesco Alessandrino, Angela Giardino, Nikhil Ramaiya, Katherine Krajewski
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Cancer Imaging, Vol 18, Iss 1, Pp 1-11 (2018)
Druh dokumentu: article
ISSN: 1470-7330
DOI: 10.1186/s40644-018-0146-8
Popis: Abstract The last 5 years have been marked by profound innovation in the targeted treatment of chronic lymphocytic leukemia (CLL) and indolent lymphomas. Using CLL as a case study, we present a timeline and overview of the current treatment landscape for the radiologist, including an overview of clinical and radiological features of CLL, discussion of the targeted agents themselves, and the role of imaging in response and toxicity assessment. The goal is to familiarize the radiologist with multiple Food and Drug Administration (FDA)-approved targeted agents used in this setting and associated adverse events which are commonly observed in this patient population.
Databáze: Directory of Open Access Journals