Malignant syphilis in a young woman: A case report

Autor: Jia-Qi Chen, Yue-Lan Cao, Xiao-Yong Man
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of International Medical Research, Vol 50 (2022)
Druh dokumentu: article
ISSN: 1473-2300
03000605
DOI: 10.1177/03000605221131368
Popis: Malignant syphilis (MS) is a rare dermatological manifestation of secondary syphilis. This case report describes a young woman that presented with a 15-day history of generalized condyloma lata and seborrheic dermatitis-like lesions at various stages. Laboratory tests showed a toluidine red unheated serum test titre of 1:128 and Treponema pallidum particle agglutination positivity. Serology for HIV antibodies was repeatedly negative. MS was diagnosed according to established MS diagnostic criteria. The lesions regressed after treatment with 2 400 000 units penicillin G benzathine by intramuscular injection weekly for three consecutive weeks. MS is more frequently associated with HIV-infected patients, which makes this current case more interesting because MS in HIV-negative patients has rarely been reported.
Databáze: Directory of Open Access Journals