Different care mode alter composition and function of gut microbiota in cerebral palsy children

Autor: Jinli Lyu, Xiaowei Zhang, Shenghua Xiong, Hui Wu, Jing Han, Yongjie Xie, Feifeng Qiu, Zhenyu Yang, Congfu Huang
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Frontiers in Pediatrics, Vol 12 (2024)
Druh dokumentu: article
ISSN: 2296-2360
06289592
DOI: 10.3389/fped.2024.1440190
Popis: IntroductionSpecialized care is essential for the recovery of children with cerebral palsy (CP). This study investigates how different care modes impact the gut microbiota.MethodsFecal samples from 32 children were collected, among whom those cared for by family (n = 21) were selected as the observation group, and those cared for by children's welfare institutions (n = 11) were selected as the control group (registration number of LGFYYXLL-024). The gut microbiota profiles were analyzed.ResultsThere was no significant difference in the α-diversity of the gut microbiota and the abundance at the phylum level. However, at the genus level, the observation group showed a significant increase in the abundance of butyrate-producing bacteria Bacteroides and Lachnospiracea incertae sedis (P
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