Symposium 13: Impact of prediabetes on macrovascular disease

Autor: Carolina Gómez Martin
Jazyk: Spanish; Castilian
Rok vydání: 2022
Předmět:
Zdroj: Revista de la Sociedad Argentina de Diabetes, Vol 56, Iss 3Sup, Pp 82-82 (2022)
Druh dokumentu: article
ISSN: 0325-5247
2346-9420
DOI: 10.47196/diab.v56i3Sup.621
Popis: Macrovascular complications are often present at the time of diagnosis of type 2 diabetes: in a retrospective study that included 159,736 people newly diagnosed with diabetes, 23.5% had at least one macrovascular complication (coronary, cerebrovascular, and/or peripheral arterial disease)1. Epidemiological studies have shown that prediabetes is a strong predictor of cardiovascular disease (CVD). In a meta-analysis including 53 prospective cohort studies with 1,611,339 individuals, with a follow-up of 9.5 years, prediabetes was associated with an increased risk of CVD, coronary heart disease, stroke and all-cause mortality compared with normoglycemia2. In this sense, the EPIC-Norfolk study showed that a 1% increase in HbA1c within the normal range was associated with greater cardiovascular mortality at ten years3.
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