Decreased amygdala volume in adults after premature birth

Autor: Benita Schmitz-Koep, Juliana Zimmermann, Aurore Menegaux, Rachel Nuttall, Josef G. Bäuml, Sebastian C. Schneider, Marcel Daamen, Henning Boecker, Claus Zimmer, Dieter Wolke, Peter Bartmann, Dennis M. Hedderich, Christian Sorg
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Druh dokumentu: article
ISSN: 2045-2322
DOI: 10.1038/s41598-021-84906-2
Popis: Abstract Premature-born infants have impaired amygdala structure, presumably due to increased stress levels of premature birth mediated by the amygdala. However, accounting for lifelong plasticity of amygdala, it is unclear whether such structural changes persist into adulthood. To address this problem, we stated the following questions: first, are whole amygdala volumes reduced in premature-born adults? And second, as adult anxiety traits are often increased after prematurity and linked with amygdala structure, are alterations in amygdala associated with adults’ anxiety traits after premature birth? We addressed these questions by automated amygdala segmentation of MRI volumes in 101 very premature-born adults (
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