Treatment of rocuronium-induced anaphylaxis using sugammadex - A case report

Autor: Sun-Min Kim, Sei-hoon Oh, Seung-Ah Ryu
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Anesthesia and Pain Medicine, Vol 16, Iss 1, Pp 56-59 (2021)
Druh dokumentu: article
ISSN: 1975-5171
2383-7977
DOI: 10.17085/apm.20074
Popis: Background Perioperative anaphylaxis is a life-threatening clinical condition characterized by severe respiratory and cardiovascular manifestations. Neuromuscular blocking agents are the most common cause of anaphylaxis during anesthesia. Case We report a case of rocuronium-induced anaphylaxis treated with sugammadex. A 75-year-old female was scheduled to undergo spinal surgery. She had no history of allergies. After the injection of rocuronium, she developed hypotension and tachycardia, and skin rashes and urticaria appeared. The patient received sugammadex to delay the operation, and her vital signs were stabilized. On the 76th postoperative day, we performed intradermal tests for rocuronium, propofol, and cefazolin. Diluted rocuronium alone induced 14 mm of flare and 8 mm of wheal within 5 min, both of which disappeared within 15 min after the intradermal injection. Conclusions Sugammadex is a useful rocuronium antagonist that can be used to treat rocuronium-induced anaphylaxis.
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