Clinical–Pathological Features of Thyroid Neoplasms in Young Patients Diagnosed in a Single Center

Autor: Aura Jurescu, Dan Brebu, Alexandra Corina Faur, Octavia Vita, Robert Barna, Adrian Vaduva, Oana Popa, Anca Muresan, Mihaela Iacob, Marioara Cornianu, Remus Cornea
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Life, Vol 14, Iss 6, p 696 (2024)
Druh dokumentu: article
ISSN: 2075-1729
DOI: 10.3390/life14060696
Popis: Background and objectives: The aim of this study was to evaluate the clinical–pathological profile in young patients with thyroid cancer. Materials and methods: We realized a retrospective study on patients with thyroid neoplasms who underwent surgery at the “Pius Brinzeu” County Clinical Emergency Hospital in Timisoara, Romania. A comparative analysis of some parameters between two groups, young patients (Results: A total of 211 patients met the study inclusion criteria, mostly females (86.26%) with a female/male ratio of 6.81:1. In patients 1 cm; 13.46% had extrathyroidal extension (p = 0.0430); 21.15% capsule invasion (p = 0.1756); 23.08% lympho-vascular invasion (p = 0.0048); and 13.46% of cases locoregional nodal invasion (p = 0.0092). Conclusions: Thyroid cancer in young people was associated with chronic lymphocytic thyroiditis and tumor progression parameters, identifying more cases of extrathyroidal extension, locoregional nodal invasion, lympho-vascular invasion and perineural invasion in young patients compared to older ones. For a better understanding of this pathology and to improve diagnosis and therapeutic management, more studies are needed for these patients.
Databáze: Directory of Open Access Journals
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