Case series of cranial and spinal dysraphism

Autor: Gayathri Pandurangam, D Nagajyothi, Seethamsetty Saritha, Asra Anjum
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: National Journal of Clinical Anatomy, Vol 11, Iss 2, Pp 110-112 (2022)
Druh dokumentu: article
ISSN: 2277-4025
2321-2780
DOI: 10.4103/NJCA.NJCA_120_21
Popis: Neural tube defects (NTDs) are the second most common cause of congenital anomaly worldwide (cardiac anomalies is the first). The 3rd and 4th week of gestation is the critical period for neural tube development. Multiple genetic and environmental factors are known to cause the NTDs in a developing embryo. We report here four cases of cranial and spinal dysraphism or craniorachischisis, the most severe and rare type of NTD with brief maternal history. In all these cases, the neural tissue is exposed in the region of brain as well as in the region of spinal cord to various extents. In this case series, the external features of craniorachischisis in four female fetuses (including monozygotic twins) are reported. One of the affected fetuses had associated omphalocele.
Databáze: Directory of Open Access Journals