Potential effect of green tea extract for adjuvant treatment of acute ischemic stroke by s100ß upregulation in non-thrombolysis patient
| Autor: | Abdulloh Machin, Djoko Agus Suprapto, Anny Hanifah, Isti Suharjanti, Jakfar Shodiq, M Fata Fatihuddin, Beom Joon Kim, Azizah Amimathul Firdha |
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| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Jurnal Ners, Vol 18, Iss 2, Pp 145-153 (2023) |
| Druh dokumentu: | article |
| ISSN: | 1858-3598 2502-5791 |
| DOI: | 10.20473/jn.v18i2.45537 |
| Popis: | Introduction: In ischemic stroke, the cerebral cortex suffers from hypoxia-ischemia, leading to inflammation and oxidative stress. Green tea extract has an anti-inflammation effect and antioxidant. This study aimed to determine the efficacy of green tea extract for adjuvant treatment of acute ischemic stroke in non-thrombolysis patients. Methods: A double-blind randomised controlled trial was conducted in November 2020-November 2021. The subjects were all acute ischemic stroke patients who presented to the Emergency Room during recruitment, randomised into control (n=13) and intervention groups (n=18); the intervention groups were given green tea extract 350 mg. Treatment was for 30 days. National Institutes of Health Stroke Scale (NIHSS), modified Rankin Scale (mRS), Montreal Cognitive Assessment - Indonesia (MoCAIna), IL-10 and S100ß were analysed. Results: Data were compared with a significance level of p |
| Databáze: | Directory of Open Access Journals |
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