Prognostic factors and survival outcome of primary pulmonary acinar cell carcinoma

Autor: Fan‐jie Meng, Zhao‐nan Sun, Zhi‐Na Wang, Hong‐Ming Ma, Wen‐cheng Zhang, Zhou‐yong Gao, Lin‐lin Ji, Fu‐kai Feng, Bo Yang, Chun‐yang Wang, Zi‐yi Chen, Nan Zhang, Guang‐shun Wang
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Thoracic Cancer, Vol 12, Iss 18, Pp 2439-2448 (2021)
Druh dokumentu: article
ISSN: 1759-7714
1759-7706
DOI: 10.1111/1759-7714.14086
Popis: Abstract Purpose The objective of our study was to investigate the epidemiologic characteristics and prognostic factors in patients with pulmonary acinar cell carcinoma (PACC). Methods PACC patients diagnosed between 1975 and 2016 were identified from the Surveillance, Epidemiology, and End Results (SEER) database. The trend in PACC incidence was assessed using joinpoint regression software. Overall survival (OS) and disease‐specific survival (DSS) were evaluated using the Kaplan–Meier method and log‐rank test. Univariate and multivariate Cox regression analysis was performed to identify the independent prognostic factors for OS and DSS. Nomograms to predict survival possibilities were constructed based on the identified independent prognostic factors. Results A total of 2918 patients were identified with PACC. The mean age was 65.2 ± 8.95 years with a female to male of 1.6:1. The incidence of PACC steadily increased by an annual percentage change (APC) of 3.2% (95% CI 2.1–4.4, p
Databáze: Directory of Open Access Journals
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