Assessment of Vitex agnus- castus L. Extract Effect on Treatment of Premenstrual Syndrome
| Autor: | M Pakgohar, Moradi M, AH Jamshidi, A Mehran |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2009 |
| Předmět: | |
| Zdroj: | Journal of Medicinal Plants, Vol 8, Iss 32, Pp 98-107 (2009) |
| Druh dokumentu: | article |
| ISSN: | 2717-204X 2717-2058 |
| Popis: | Background: Premenstrual syndrome is a cyclic recurrence of the luteal phase of the menstrual cycle of combination of distressing physical, psychological of sufficient severity to result in deterioration of interpersonal relationships and /or interference with normal activities. Traditionally, Vitex agnus castus fruit extract has been used in the treatment of many female conditions. Objective: Assess of Vitex agnus - castus effect (4.3 – 4.8mg dry extract) on treatment of premenstrual syndrome. Methods: Randomized, double blind, placebo controlled, parallel group comparison over two menstrual cycles on students of Tehran Medical University and Tehran University, that live in dormitory. Volunteers under vent a preliminary screening interview, completed Daily Symptom Rating (DSR) (contain 18 symptoms) for two cycle, and attended a medical screening visit before being diagnosed with premenstrual syndrome and screening for depression by Beck questionary. 116 students were screened and 99 were evaluated (active: 49 placebo: 50). Participants took Vitex agnus - castus (dry extract tablets) one tablet daily or matching placebo for two cycles. Data were analyzed by descriptive and analytic statistics (chi-square, fisher exact test, willcoxon, mann- whitney u and t test). Results: Decrease of severity of premenstrual syndrome was significantly greater in the Vitex group compared with placebo group in total symptoms of premenstrual syndrome (60.73% versus 20.79%, p |
| Databáze: | Directory of Open Access Journals |
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