Basic coagulation parameters and platelet count among malaria patients attending at Addis Zemen Primary Hospital, Northwest Ethiopia

Autor: Tegenaw Tiruneh, Andargachew Almaw, Aynework Abebaw, Teklehaimanot Kiros, Ayenew Berhan, Shewaneh Damtie, Biruk Legese, Dejen Getaneh Feleke, Meslo Sema, Ermias Sisay Chanie, Tadila Dires, Desalegn Andargie, Barnabas Achaw, Tahir Eyayu
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-10 (2024)
Druh dokumentu: article
ISSN: 1471-2334
DOI: 10.1186/s12879-024-09944-3
Popis: Abstract Background Malaria is an intravascular parasitic-related blood disease that causes bleeding, coagulopathy, and thrombocytopenia. However, limited data shows the effect of Plasmodium species infection on basic coagulation parameters and platelet count. Thus, this study aimed to assess basic coagulation parameters and platelet count among malaria patients. Method A cross-sectional study was conducted among 240 study participants (120 cases and 120 controls) from June 1, 2021, to February 30, 2022. A convenient sampling technique was employed to select study participants. The blood sample was collected by a trained laboratory technologist for platelet counts, prothrombin time (PT), partial thromboplastin time (PTT), international normalization ratio (INR), blood film, and serological testing. The collected data were analyzed in SPSS version 23. Data were analyzed by the Mann-Whitney U test, Kruskal Wallis H, and Spearman’s rank-order correlation tests. Descriptive findings were presented through median, tables, and chart. In all cases, a P-value
Databáze: Directory of Open Access Journals
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