The rationale for antidepressants in the treatment of schizophrenia: A modern view on the problem in the context of evidence-based medicine

Autor:	D. S. Danilov, D. O. Magomedova, M. E. Matsneva
Jazyk:	ruština
Rok vydání:	2016
Předmět:	antidepressants selective serotonin reuptake inhibitors schizophrenia depression negative symptoms obsessive-phobic (obsessivecompulsive) symptoms evidence-based medicine observational studies Neurology. Diseases of the nervous system RC346-429
Zdroj:	Неврология, нейропсихиатрия, психосоматика, Vol 8, Iss 1, Pp 71-81 (2016)
Druh dokumentu:	article
ISSN:	2074-2711 2310-1342
DOI:	10.14412/2074-2711-2016-1-71-81
Popis:	The paper discusses whether antidepressant treatment is rational in schizophrenics. It analyzes the results from trials evaluating the efficiency of the therapy in patients with depressive, negative, or obsessive-phobic symptoms. The validity of results of these trials is assessed. The results of demonstrative trials of the efficiency of therapy with different representatives of antidepressants (selective serotonin reuptake inhibitors) in the above patient groups are given separately and compared with the data obtained in observational studies. Emphasis is placed on the criticism of shortages of procedures and results of demonstrative trials conducted in foreign countries. Prospects for further trials evaluating the efficiency of antidepressant therapy for schizophrenia are depicted.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/74b5206fefbc433d8b7fcd8f192c5f3f Zobrazit plný text záznamu View record in DOAJ