Influence of fixed combination perindopril and indapamide on heart and vascular remodeling in hypertensive patients

Autor:	Yu. M. Lopatin, T. D. Каplanov, V. V. Ivanenko, N. V. Ryazantseva, A. V. Legky, L. P. Anisimova
Jazyk:	ruština
Rok vydání:	2005
Předmět:	arterial hypertension fixed perindopril/indapamide combination cardiovascular remodeling Diseases of the circulatory (Cardiovascular) system RC666-701
Zdroj:	Кардиоваскулярная терапия и профилактика, Vol 4, Iss 1, Pp 20-25 (2005)
Druh dokumentu:	article
ISSN:	1728-8800 2619-0125
Popis:	Aim. To evaluate antihypertensive efficacy of fixed combination: perindopril 4 mg/d plus indapamide 1.25 mg/d, and its influence on cardiovascular remodeling in untreated hypertensive patients. Material and methods. The study included 25 previously untreated patients with arterial hypertension (mean age 48.1±2,7 years; 13 males, 12 females). The effects of 6-month perindopril/indapamide combined therapy on daily blood pressure (BP), left ventricular (LV) hypertrophy, carotid intima-media thickness (IMT), pulse wave velocity (PWV), and cerebral blood flow velocity were investigated. Results. Target BP level was achieved in 77% of the patients. BP monitoring demonstrated significant reduction in systolic BP (daytime: -9.4%, p
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/74aa7a3958a34fdfa259e0970e833b1b Zobrazit plný text záznamu View record in DOAJ