Orbitofrontal sulcal patterns in catatonia
| Autor: | Mylène Moyal, Alexandre Haroche, David Attali, Ghita Dadi, Matthieu Raoelison, Alice Le Berre, Anton Iftimovici, Boris Chaumette, Sylvain Leroy, Sylvain Charron, Clément Debacker, Catherine Oppenheim, Arnaud Cachia, Marion Plaze |
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| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | European Psychiatry, Vol 67 (2024) |
| Druh dokumentu: | article |
| ISSN: | 0924-9338 1778-3585 |
| DOI: | 10.1192/j.eurpsy.2023.2461 |
| Popis: | Abstract Background Catatonia is a psychomotor syndrome frequently observed in disorders with neurodevelopmental impairments, including psychiatric disorders such as schizophrenia. The orbitofrontal cortex (OFC) has been repeatedly associated with catatonia. It presents with an important interindividual morphological variability, with three distinct H-shaped sulcal patterns, types I, II, and III, based on the continuity of the medial and lateral orbital sulci. Types II and III have been identified as neurodevelopmental risk factors for schizophrenia. The sulcal pattern of the OFC has never been investigated in catatonia despite the role of the OFC in the pathophysiology and the neurodevelopmental component of catatonia. Methods In this context, we performed a retrospective analysis of the OFC sulcal pattern in carefully selected homogeneous and matched subgroups of schizophrenia patients with catatonia (N = 58) or without catatonia (N = 65), and healthy controls (N = 82). Results Logistic regression analyses revealed a group effect on OFC sulcal pattern in the left (χ 2 = 18.1; p |
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