Blood eosinophils levels in a Colombian cohort of biomass-and tobacco-related COPD patients

Autor: Olga Milena García Morales, Alejandra Cañas-Arboleda, María Nelcy Rodríguez Malagón, Javier Leonardo Galindo Pedraza, Paola Rodríguez Torres, Violeta Rosa Avendaño Morales, Andrés Leonardo González-Rangel, Carlos A. Celis-Preciado
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Frontiers in Medicine, Vol 11 (2024)
Druh dokumentu: article
ISSN: 2296-858X
DOI: 10.3389/fmed.2024.1321371
Popis: IntroductionChronic obstructive pulmonary disease (COPD) is a major cause of illness and death among adults. In 2019, the Global Initiative for Chronic Obstructive Lung Disease (GOLD) strategy incorporated blood eosinophils as a biomarker to identify patients at increased risk of exacerbations which, with the history of exacerbations during the previous year, allows identification of patients who would benefit from anti-inflammatory treatment to reduce the risk of future exacerbations. The aim of this study was to describe demographic and clinical characteristics, eosinophil counts, and exacerbations in a cohort of COPD patients stratified by clinical phenotypes (non-exacerbator, frequent exacerbator, asthma-COPD overlap) in a Colombian cohort at 2600 meters above sea level.MethodsA descriptive analysis of a historical cohort of patients with a confirmed diagnosis of moderate to severe COPD (FEV1/FVC
Databáze: Directory of Open Access Journals