Colostrum supplement, immune variables and hospital-acquired infection in acute respiratory failure: A double-blind, randomized, placebo-controlled study

Autor: Elham Roohelhami, Seyed Hossein Ardehali, Elham Makiabadi, Zahra Vahdat Shariatpanahi
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Functional Foods, Vol 111, Iss , Pp 105909- (2023)
Druh dokumentu: article
ISSN: 1756-4646
DOI: 10.1016/j.jff.2023.105909
Popis: Background: Bovine colostrum has anti-microbial and immunomodulatory properties. We investigated the possibility of colostrum supplementation for managing hospital-acquired infections in critically ill patients. Materials & methods: Patients with enteral nutrition were randomly assigned to receive either colostrum 30 g daily in the intervention group or a similar amount of formula in the control group for ten days. Results: GEE-analysis showed that patients in the colostrum group (n = 45) had higher serum CD4 and CD8 protein levels by 0.33 ng/ml and 0.29 ng/ml respectively than the control group (n = 45) during the study period (P
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