Lung adenocarcinoma patients with ROS1-rearranged tumors by sex and smoking intensity

Autor: Yanmei Peng, Vinicius Ernani, Dan Liu, Qian Guo, Markay Hopps, Joseph C. Cappelleri, Ruchi Gupta, Mariza de Andrade, Jun Chen, Eunhee S. Yi, Ping Yang
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Heliyon, Vol 10, Iss 7, Pp e28285- (2024)
Druh dokumentu: article
ISSN: 2405-8440
DOI: 10.1016/j.heliyon.2024.e28285
Popis: Background: ROS1 rearrangements (ROS1+) define a distinct molecular subset of lung adenocarcinomas. ROS1 + tumors are known to occur more in never-smokers, but the frequency and outcome of ROS1 positivity by sex and smoking intensity are not clearly documented. Patients and methods: This patient cohort study included all never- (
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