BRAF Expression and Copy Number Alterations Predict Unfavorable Tumor Features and Adverse Outcomes in Patients With Breast Cancer

Autor: Yazan R. Alhamdan, Nehad M. Ayoub, Sara K. Jaradat, Aymen Shatnawi, Rami J. Yaghan
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: International Journal of Breast Cancer, Vol 2024 (2024)
Druh dokumentu: article
ISSN: 2090-3189
DOI: 10.1155/2024/6373900
Popis: Conclusion: High BRAF mRNA expression as well as the gain and high-level amplification copy numbers were associated with advanced tumor characteristics and unfavorable prognostic factors in breast cancer. BRAF could be an appealing target for the treatment of premenopausal patients with hormone receptor–negative breast cancer.
Databáze: Directory of Open Access Journals
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