Stereodivergent propargylic alkylation of enals via cooperative NHC and copper catalysis

Autor: Yu-Hua Wen, Zi-Jing Zhang, Shuai Li, Jin Song, Liu-Zhu Gong
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-022-29059-0
Popis: The ability to construct multiple stereocenters in a modular fashion is an important goal of synthetic organic chemistry. Here the authors present a method to construct oxindoles in four stereoisomers with high enantioselectivity and diastereoselectivity from the same starting materials by using cooperative copper- and organocatalysis.
Databáze: Directory of Open Access Journals