Centrosomal protein72 rs924607 and vincristine-induced neuropathy in pediatric acute lymphocytic leukemia: meta-analysis

Autor: Aida Zečkanović, Janez Jazbec, Marko Kavčič
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Future Science OA, Vol 6, Iss 7 (2020)
Druh dokumentu: article
ISSN: 2056-5623
DOI: 10.2144/fsoa-2020-0044
Popis: Aim: We examined the utility of the rs924607 TT genotype of the centrosomal protein 72 (CEP72) as a potential biomarker for predilection toward vincristine-induced peripheral neuropathy in children treated for acute lymphoblastic leukemia. Materials & methods: We conducted a random-effects meta-analysis of data from four studies comprising 817 patients. We tested for an association using a recessive model where a one-sided p-value
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