| Autor: |
Chanon Ngamsombat, M.D., Thanapat Dechasasawat, M.D., Jitsupa Wongsripuemtet, M.D., Panida Charnchaowanish, B.Sc., Weerasak Muangpaisan, M.D., Orasa Chawalparit, M.D. |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Siriraj Medical Journal, Vol 71, Iss 2, Pp 117-122 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
2228-8082 |
| DOI: |
10.33192/Smj.2019.18 |
| Popis: |
Objective: Posterior cingulate gyrus atrophy is found in early clinical stage of Alzheimer’s disease (AD) patients.1 Diffusion tensor imaging (DTI) can be used for evaluating microstructure change in brain parenchyma.2 Our objective was to compare the microstructural change at posterior cingulate gyrus between AD patients and normal control subjects by using DTI. Methods: The retrospective review of 23 AD patients, diagnosed by NINCDS-ADRDA with available MRI data including DTI, and 19 normal control subjects was performed. The DTI parameters of posterior cingulate gyrus of each group were analyzed and compared. Results: The mean diffusivity (MD), axial diffusivity and radial diffusivity (RD) of posterior cingulate gyrus were significantly increased in AD patients compared with normal control subjects (p-value |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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